|
T7633 |
Senktide
|
|
Neurokinin receptor
|
|
Senktide is an agonist of tachykinin NK3 receptor. |
|
TP1087 |
Substance P
|
Neurokinin P |
Endogenous Metabolite
,
Neurokinin receptor
|
|
Substance P (Neurokinin P) (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family. |
|
T7209 |
Maropitant
|
|
Neurokinin receptor
|
|
Maropitant is a selective neurokinin (NK1) receptor antagonist. |
|
TP1572 |
GR-73632
|
|
Neurokinin receptor
|
|
Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). |
|
T38144 |
Elinzanetant
|
|
Neurokinin receptor
|
|
Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion. |
|
T15278 |
Fezolinetant
|
ESN-364 |
Neurokinin receptor
|
|
Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R). It is used for the treatment of menopausal hot flushes. |
|
T23316 |
SB 218795
|
|
Neurokinin receptor
|
|
SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1. |
|
T7549 |
Talnetant
|
SB 223412 |
Neurokinin receptor
|
|
Talnetant (SB 223412) is a selective, competitive, brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission |
|
T16849 |
SB-222200
|
|
Neurokinin receptor
|
|
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM). |
|
T8235 |
L-732138
|
|
Neurokinin receptor
|
|
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM) |
|
TP1883 |
[Lys5,MeLeu9,Nle10]-NKA(4-10)
|
|
Neurokinin receptor
|
|
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively). |
|
T17156 |
Tradipitant
|
VLY-686,LY686017 |
Neurokinin receptor
|
|
Tradipitant (VLY-686) is an antagonist of neurokinin-1. |
|
T7554 |
Substance P (7-11)
|
Substance P 7-11(TFA) |
Others
,
Neurokinin receptor
|
|
Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P . |
|
T3716 |
Rolapitant
|
SCH619734 |
Neurokinin receptor
|
|
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ... |
|
T6905 |
Netupitant
|
Ro 67-31898/000,CID 6451149 |
Neurokinin receptor
|
|
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM). |
|
TP1008 |
Neurokinin A
|
α-Neurokinin,Substance K,Neuromedin L |
Neurokinin receptor
|
|
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene. |
|
T1743 |
Aprepitant
|
MK-869,MK-0869,L-754030,Aprepitant` |
HIV Protease
,
Antibacterial
,
Antibiotic
,
Neurokinin receptor
|
|
Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and C... |
|
T13306L |
Vapreotide acetate
|
RC-160 acetate,BMY-41606 acetate |
Neurokinin receptor
|
|
Vapreotide acetate (BMY-41606 acetate) is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM). |
|
T3034 |
Eprazinone dihydrochloride
|
Resplen,Mucitux,Eftapan,NSC 317935,Eprazinone 2HCl |
Others
,
Neurokinin receptor
|
|
Eprazinone dihydrochloride (NSC 317935) is a mucolytic with antitussive and mucolytic effect. |
|
T1790 |
Fosaprepitant dimeglumine
|
L785298,MK-0517,Fosaprepitant dimeglumine salt |
Neurokinin receptor
|
|
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion... |
|
T7828 |
[Sar9,Met(O2)11]-Substance P
|
Bhsar-sp,NA |
Neurokinin receptor
|
|
[Sar9,Met(O2)11]-Substance P (NA) is an agonist of NK1 receptor. |
|
T7396 |
Substance P(1-7)
|
Substance P 1-7 |
Others
,
Neurokinin receptor
|
|
Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects |
|
T7631 |
Eledoisin Related Peptide
|
Eledoisin RP,Eledoisin-Related Peptide,Eledoisin Related Peptide(2TFA) |
Neurokinin receptor
|
|
Eledoisin Related Peptide (Eledoisin RP) is a tachykinin receptor ligand. |
|
T7559 |
Neurokinin A(4-10)
|
Neurokinin A(4-10)(TFA) |
Neurokinin receptor
|
|
Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor . |
|
T24697L |
R 396 acetate
|
|
Neurokinin receptor
|
|
R 396 acetate is an NK-2 Tachykinin Receptor
Antagonist. |
|
TP1385 |
Neurokinin A(4-10) TFA(97559-35-8 free base)
|
Neurokinin A(4-10) TFA |
Neurokinin receptor
|
|
Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1]. |
|
T14524 |
Befetupitant
|
Ro67-5930 |
Neurokinin receptor
|
|
Befetupitant (Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization. |
|
T24446L |
MEN 10207 acetate
|
|
Neurokinin receptor
|
|
MEN 10207 acetate is a selective antagonist for NK-2 tachykinin receptor. |
|
T7631L |
Eledoisin Related Peptide 2TFA
|
Eledoisin Related Peptide 2TFA(2990-43-4(free base)) |
Neurokinin receptor
|
|
Eledoisin Related Peptide 2TFA (Eledoisin Related Peptide 2TFA (2990-43-4(free base))) is a tachykinin receptor ligand. |
|
T69140 |
Burapitant
|
SSR 240600 |
Neurokinin receptor
|
|
Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity. |
|
T19518L |
Physalaemin acetate
|
|
Neurokinin receptor
|
|
Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor. |
|
T12000 |
MEN11467
|
|
Neurokinin receptor
|
|
|
|
TP1086 |
Men 10376 TFA(135306-85-3,free)
|
Men 10376 TFA,Neurokinin-2 receptor antagonist TFA |
Neurokinin receptor
|
|
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats. |
|
TP1363L |
Neurokinin B acetate(86933-75-7 free base)
|
Neurokinin K |
Neurokinin receptor
|
|
Neurokinin B acetate(86933-75-7 free base) is the acetate form of Neurokinin B, which belongs to the tachykinin family. Neurokinin binds to neurokinin receptor 1 (NK1R), nk2r and NK3R, and mediates its biological effects... |
|
TP1369L |
[Sar9,Met(O2)11]-Substance P acetate
|
[Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base) |
Neurokinin receptor
|
|
[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (1... |
|
T13329L |
Vofopitant dihydrochloride
|
GR 205171A,Vofopitant 2HCl |
Neurokinin receptor
|
|
Vofopitant dihydrochloride (GR 205171A) is an orally available, selective tachykinin NK1 receptor antagonist that inhibits [3H]SP binding to NK1 with pKi values of 9.5 and 10.6, respectively.Vofopitant dihydrochloride is... |
|
TP1899L1 |
Hemokinin 1 (human) acetate(491851-53-7 free base)
|
|
Neurokinin receptor
|
|
Hemokinin 1 (human) acetate is an endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has prolifera... |
|
TP1931L1 |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
|
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base) |
cholecystokinin
|
|
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist ... |
|
T9417L |
Gamma-preprotachykinin amide (72-92) acetate
|
gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base) |
Others
|
|
gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate po... |
|
T16039 |
Ibodutant
|
MEN 15596 |
Others
|
|
Ibodutant is an effective and selective tachykinin NK2 receptor antagonist (pKi: 10.1). |
|
T23345 |
SDZ NKT 343
|
|
Others
|
|
human tachykinin NK1 receptor antagonist |
|
T22811 |
GR 94800
|
|
Others
|
|
Potent and selective tachykinin NK2 receptor antagonist |
|
T23251 |
RP 67580
|
|
Others
|
|
tachykinin NK1 receptor antagonist |
|
T26333 |
WS 9326A
|
WS9326A,WS-326A |
|
|
WS 9326A is an antagonist of tachykinin receptor from Streptomyces violaceusniger. |
|
T22786 |
FK 888
|
|
Others
|
|
FK 888 is a selective, high-affinity tachykinin NK1 receptor antagonist. |
|
T20148 |
L 659,877
|
L 659877,L-659,877,L-659877,L659,877,L659877 |
|
|
L 659,877 is an antagonist of the Tachykinin and neurokinin-2 receptor. |
|
T25419 |
FK 224
|
FK-224,FK224 |
|
|
FK 224 is an antagonist of tachykinin receptor. |
|
T70416 |
PD 154075
|
|
|
|
PD 154075 is a a non-peptide tachykinin NK1 receptor antagonist. |
|
T28917 |
TAK-637
|
TAK 637 |
|
|
TAK-637 is a tachykinin 1 (NK1) receptor antagonist. |
|
T27175 |
Dilopetine Citrate
|
E-6006 Citrate,E-6039,E6039,E 6039 |
|
|
Dilopetine Citrate, a tachykinin receptor modulator and a neurokinin receptor modulator, is used potentially for the treatment of depression. |
